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    • 10 hours, 51 minutes ago
      Amanda Barras likes your comment at
      Have you heard about tegoprupart, an immunosuppressant alternative with fewer side effects than traditional immunosuppressants, now being used for islet cell transplantation?
      I follow Katie Beth Hand and Crushingt1 lots of great info on the Eledon trial. I would definitely sign up for the trial if I was eligible.
    • 10 hours, 51 minutes ago
      Amanda Barras likes your comment at
      Have you heard about tegoprupart, an immunosuppressant alternative with fewer side effects than traditional immunosuppressants, now being used for islet cell transplantation?
      I'd sign up today!!!!! Have to admit that listening to her describe her "freedom" with "no longer having" T1D makes me jealous!
    • 10 hours, 54 minutes ago
      Amanda Barras likes your comment at
      Have you heard about tegoprupart, an immunosuppressant alternative with fewer side effects than traditional immunosuppressants, now being used for islet cell transplantation?
      I was shocked that so many people haven't heard about it. It is all over social media. It looks promising to me. Of course the trial participants need to be followed for awhile as no drug gets approved by the FDA in short time, but so far all of the first 12 trial participants are insulin free and the 1st participant has been insulin free for over 1-1/2 years with no complications that I've heard of.
    • 12 hours, 58 minutes ago
      Anita Stokar likes your comment at
      Have you heard about tegoprupart, an immunosuppressant alternative with fewer side effects than traditional immunosuppressants, now being used for islet cell transplantation?
      I'd sign up today!!!!! Have to admit that listening to her describe her "freedom" with "no longer having" T1D makes me jealous!
    • 12 hours, 58 minutes ago
      Anita Stokar likes your comment at
      Have you heard about tegoprupart, an immunosuppressant alternative with fewer side effects than traditional immunosuppressants, now being used for islet cell transplantation?
      I follow Katie Beth Hand and Crushingt1 lots of great info on the Eledon trial. I would definitely sign up for the trial if I was eligible.
    • 13 hours, 40 minutes ago
      Ahh Life likes your comment at
      Have you heard about tegoprupart, an immunosuppressant alternative with fewer side effects than traditional immunosuppressants, now being used for islet cell transplantation?
      This question is an advertisement. In my opinion it is a misleading advertisement. Tegoprupart is an immunosuppressant. A trial investigating using the drug with islet cell recipients has barely gotten started. 90-ish percent of all phase 3 drug trials fail. Drug development is hard. I wish them luck at the same time I wish they weren't misleading people about the investigational use of their drug.
    • 14 hours, 43 minutes ago
      Marthaeg likes your comment at
      Have you heard about tegoprupart, an immunosuppressant alternative with fewer side effects than traditional immunosuppressants, now being used for islet cell transplantation?
      I'd sign up today!!!!! Have to admit that listening to her describe her "freedom" with "no longer having" T1D makes me jealous!
    • 14 hours, 43 minutes ago
      Marthaeg likes your comment at
      Have you heard about tegoprupart, an immunosuppressant alternative with fewer side effects than traditional immunosuppressants, now being used for islet cell transplantation?
      I follow Katie Beth Hand and Crushingt1 lots of great info on the Eledon trial. I would definitely sign up for the trial if I was eligible.
    • 16 hours, 23 minutes ago
      Gerald Oefelein likes your comment at
      Have you heard about tegoprupart, an immunosuppressant alternative with fewer side effects than traditional immunosuppressants, now being used for islet cell transplantation?
      AI Overview Tegoprubart, an anti-CD40L antibody, is generally safe and well-tolerated, with a cleaner safety profile than traditional calcineurin inhibitors (like tacrolimus) in early trials, specifically showing lower risks of kidney toxicity and diabetes. Common side effects reported include fatigue, headaches, muscle spasms, and potential infections. National Institutes of Health (.gov) National Institutes of Health (.gov) +4 Common Side Effects and Adverse Events In clinical trials, the most frequent treatment-emergent adverse events (TEAEs) observed included: National Institutes of Health (.gov) National Institutes of Health (.gov) +2 Fatigue (approx. 25.9%) Falls (approx. 22.2%) Headaches (approx. 20.4%) Muscle spasms (approx. 11.1%) Upper respiratory tract infections Sleepiness Key Safety Advantages Over Standard Care (Tacrolimus) Tegoprubart aims to avoid the, often, severe, long-term side effects of standard anti-rejection meds like tacrolimus
    • 16 hours, 24 minutes ago
      Lawrence S. likes your comment at
      Have you heard about tegoprupart, an immunosuppressant alternative with fewer side effects than traditional immunosuppressants, now being used for islet cell transplantation?
      No thanks.
    • 1 day, 12 hours ago
      Gerald Oefelein likes your comment at
      If islet cell transplantation is proven safe and effective, how likely would you be to consider it a treatment option?
      Without rejection drugs- very likely. With rejection drugs- not a chance.
    • 1 day, 12 hours ago
      Gerald Oefelein likes your comment at
      If islet cell transplantation is proven safe and effective, how likely would you be to consider it a treatment option?
      Only if I don't need to take any immunosuppression drugs
    • 1 day, 12 hours ago
      Gerald Oefelein likes your comment at
      If islet cell transplantation is proven safe and effective, how likely would you be to consider it a treatment option?
      All depends on if anti rejection and immunosuppressive medications are needed. If so I would not be interested.
    • 1 day, 12 hours ago
      Gerald Oefelein likes your comment at
      If islet cell transplantation is proven safe and effective, how likely would you be to consider it a treatment option?
      It would depend on the cost and coverage by insurance as well as the requirement for immunity suppressants.
    • 1 day, 12 hours ago
      Gerald Oefelein likes your comment at
      If islet cell transplantation is proven safe and effective, how likely would you be to consider it a treatment option?
      Very likely provided immunosuppressants aren't required. Also younger people should receive the treatment first.
    • 1 day, 12 hours ago
      Gerald Oefelein likes your comment at
      If islet cell transplantation is proven safe and effective, how likely would you be to consider it a treatment option?
      as long as it doesn't require immunosuppression, I'm interested
    • 1 day, 12 hours ago
      Gerald Oefelein likes your comment at
      If islet cell transplantation is proven safe and effective, how likely would you be to consider it a treatment option?
      If it requires immunosuppressive medication I have no interest. I'll continue to manage with insulin.
    • 1 day, 12 hours ago
      Lawrence S. likes your comment at
      If islet cell transplantation is proven safe and effective, how likely would you be to consider it a treatment option?
      Without rejection drugs- very likely. With rejection drugs- not a chance.
    • 1 day, 12 hours ago
      Lawrence S. likes your comment at
      If islet cell transplantation is proven safe and effective, how likely would you be to consider it a treatment option?
      Very likely, especially if stem-cell generated islet cells are transplanted without the need for immunosuppressants. If tegoprubart is needed and is found safe after the trials are complete, then likely.
    • 1 day, 12 hours ago
      Lawrence S. likes your comment at
      If islet cell transplantation is proven safe and effective, how likely would you be to consider it a treatment option?
      Only if I don't need to take any immunosuppression drugs
    • 1 day, 12 hours ago
      Lawrence S. likes your comment at
      If islet cell transplantation is proven safe and effective, how likely would you be to consider it a treatment option?
      All depends on if anti rejection and immunosuppressive medications are needed. If so I would not be interested.
    • 1 day, 12 hours ago
      Lawrence S. likes your comment at
      If islet cell transplantation is proven safe and effective, how likely would you be to consider it a treatment option?
      It would depend on the cost and coverage by insurance as well as the requirement for immunity suppressants.
    • 1 day, 12 hours ago
      Lawrence S. likes your comment at
      If islet cell transplantation is proven safe and effective, how likely would you be to consider it a treatment option?
      Very likely provided immunosuppressants aren't required. Also younger people should receive the treatment first.
    • 1 day, 12 hours ago
      Lawrence S. likes your comment at
      If islet cell transplantation is proven safe and effective, how likely would you be to consider it a treatment option?
      Very likely. Although the simplicity of spifflicating is often overrated. 🤓☝️
    • 1 day, 12 hours ago
      Lawrence S. likes your comment at
      If islet cell transplantation is proven safe and effective, how likely would you be to consider it a treatment option?
      as long as it doesn't require immunosuppression, I'm interested
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    If you have ever been pregnant while living with T1D, how much did your insulin needs change throughout your pregnancy?

    Home > LC Polls > If you have ever been pregnant while living with T1D, how much did your insulin needs change throughout your pregnancy?
    Previous

    For people diagnosed with T1D in 2000 or after: If you have used a CGM, how long after your diagnosis did you start using a CGM? (For those diagnosed before 2000, stay tuned for tomorrow’s question!)

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    Have the health insurance benefits offered by an employer ever caused you to accept a job or stay at a job that you otherwise would have preferred to leave?

    Sarah Howard

    Sarah Howard has worked in the diabetes research field ever since she was diagnosed with T1D while in college in May 2013. Since then, she has worked for various diabetes organizations, focusing on research, advocacy, and community-building efforts for people with T1D and their loved ones. Sarah is currently the Senior Marketing Manager at T1D Exchange.

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    25 Comments

    1. PamK

      It’s been so long that I really don’t remember! I do know that I let my blood sugar run lower than normal at the advice of my doctor.

      4 years ago Log in to Reply
    2. Kristen Clifford

      I’ve had T1D for 14 years but haven’t been pregnant yet. I’ve only been married a little less than eight months. I hope to have a baby within the next two years.

      1
      4 years ago Log in to Reply
    3. Cheryl Weaver

      Actually, my last pregnancy was in 1970, and I’m not sure. I don’t remember my Dr’s making changes to my insulin, but I think it didn’t change.

      4 years ago Log in to Reply
    4. GLORIA MILLER

      My doctor told me to get my insulin requirements down as low as I could before getting pregnant. My insulin requirements more than doubled toward the end of the pregnancy. This was in 1971.

      4 years ago Log in to Reply
    5. pru barry

      My three children were born more than fifty years ago when things were much different. I don’t remember changing my NPH doses, but with all three pregnancies, experienced extreme lows which usually occurred at night and resulted in losing consciousness and winding up in the emergency room. Happy ending: three wonderful adults in their fifties, two grandkids, and no sign of diabetes in any of them. My fifteen year old labradoodle does get four shots of insulin a day. Somehow it all evens out.

      2
      4 years ago Log in to Reply
      1. Janis Senungetuk

        Sorry your dog needs insulin 4 X day. Thumbs up for healthy kids & grandchildren! 50+ years ago we were very much in the dark ages of glucose management.

        1
        4 years ago Log in to Reply
    6. Mick Martin

      Not Applicable as I’m male and never been pregnant. 😉

      1
      4 years ago Log in to Reply
    7. Claire Tallman

      Happy and healthy baby boy born in December! My insulin needs more than doubled, and the timing of insulin and food changed too. I had an incredible team and support system, and could not have done it without them. It’s not easy, but it’s manageable, and certainly WORTH IT!

      1
      4 years ago Log in to Reply
    8. cynthia jaworski

      My insulin needs continued to rise throughout the pregnancy, and then, BOOM, dropped all the way back down at birth. All went well.

      4 years ago Log in to Reply
    9. Jneticdiabetic

      I put that I needed a little more insulin. I think it had more to with me being insatiably hungry and eating more. I did have moments where I went low unexpectedly and wondered if my beta cells were recovering or just benefiting from the baby’s pancreas.
      In
      On one occasion I was driving home from work and worried that I had forgotten to dose for a late afternoon snack. I was a little thirsty and thought for sure I was high. I almost have my self a couple unit bolus, but decided to wait until I got home to test. When I did my BG was 20 mg/dl! Thank goodness I didn’t bolus!
      That was another odd of thing about pregnancy, I tolerated much lower lows without significant impairment.

      4 years ago Log in to Reply
      1. Karen Brady

        wow good thing you didn’t give that bolus!
        Re: lows I’m the opposite, I would be in the 40s/50s and had awful low symptoms, where pre-pregnancy I would be fine at 50. So strange how we all react differently!

        4 years ago Log in to Reply
    10. RegMunro

      After a few days of COVID my use of insulin soared!. It hasn’t stopped yet 2 weeks in
      Maybe a question or two?

      4 years ago Log in to Reply
      1. Bruce Schnitzler

        I have had T1D since 1951 and have been insulin dependent since then. I had Covid-19 but was completely asymptomatic and saw no changes in insulin.

        1
        4 years ago Log in to Reply
    11. Merry Woolsey

      Both my girls were born with very low blood sugars though

      4 years ago Log in to Reply
    12. Janis Senungetuk

      In 1970 with urine testing and once a month labs I rarely knew what my glucose level was. The first trimester I had great difficulty keeping any food/drink down. Once I got beyond that my twice a day Regular/NPH increased to the point of doubling by induced delivery 6 weeks early. Our healthy baby daughter is now 52 with three adult kids of her own.

      2
      4 years ago Log in to Reply
    13. Anneyun

      It was 25 years ago so I don’t remember.

      4 years ago Log in to Reply
    14. marge slater

      It was over 50 years ago so I do not remember

      1
      4 years ago Log in to Reply
    15. Julie Nalibov

      I had been T1D for nearly 30 years when I was pregnant with my first child. After 2 decades of taking around 24u/day, it crept up to 74 by 3rd trimester- then plummeted and stayed low while breastfeeding. With second pregnancy, insulin requirements dropped to single digits & NEVER rebounded. 25 years later and 20 lbs heavier later, still take less than 15 u/day. Medical mystery according to my endo. No complaints!!

      1
      4 years ago Log in to Reply
    16. Sherrie Johnson

      It’s been 43 years for me my doctor told me keep the same schedule get exercise every day and watch your insulin because the baby will be making some and you won’t need as much. That’s exactly what I did I was on NPH twice a day and I remember I had to lower the evening dose to almost half and the morning dose by about a third

      4 years ago Log in to Reply
    17. Anita Galliher

      I got pregnant in 1969 while on one shot of long-acting Lente a day. I’d pee in a test tube and compare it with a color chart after 15 seconds every morning, but regardless of what it said, I didn’t do anything else. The next morning I’d repeat the process, take my daily dose and go about my business. Once or twice a year I’d have an A1c done at the hospital, and my doctor (family doctor, not a specialist) might adjust my insulin or not. I didn’t start taking more than one shot a day, have an endocrinologist or test regularly until I was in my 40s. At 73, it’s a wonder I’m alive now, much less with nothing major wrong with me (other than T1D, of course!)

      1
      4 years ago Log in to Reply
    18. Molly Jones

      I chose other as 18yrs ago I didn’t make it past the four months of pregnancy.
      I was having more hypoglycemic events and was prescribed my first Medtronic pump.

      4 years ago Log in to Reply
    19. Melinda Lipe

      Horrible extreme highs and lows.

      1
      4 years ago Log in to Reply
      1. Karen Brady

        same! really frustrating and (mentally & physically) exhausting

        4 years ago Log in to Reply
    20. Amy Jo

      Needs slowly increased so that I:C ratio was about 5x more by the end of pregnancy, until the last couple of weeks before delivery when needs started decreasing (because the placenta was wearing out).

      4 years ago Log in to Reply
    21. marmcs@yahoo.com

      I got pregnant 8 months after diagnosis in 1991. Then had my 2nd 17 months later. Both times I was on 2 shots per day, Reg & NPH in 1 syringe. Was never told to increase insulin. Told to take my blood sugar 1.5-2 hours after eating and important to keep below 180. It never stayed below 180 after a meal but would come crashing very low after my correction. Thankful to God that my babies were both healthy and only 6.5 and 6.6 pounds at 38 weeks.

      4 years ago Log in to Reply

    If you have ever been pregnant while living with T1D, how much did your insulin needs change throughout your pregnancy? Cancel reply

    You must be logged in to post a comment.




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