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    • 1 hour, 24 minutes ago
      Gerald Oefelein likes your comment at
      Have you heard about tegoprupart, an immunosuppressant alternative with fewer side effects than traditional immunosuppressants, now being used for islet cell transplantation?
      AI Overview Tegoprubart, an anti-CD40L antibody, is generally safe and well-tolerated, with a cleaner safety profile than traditional calcineurin inhibitors (like tacrolimus) in early trials, specifically showing lower risks of kidney toxicity and diabetes. Common side effects reported include fatigue, headaches, muscle spasms, and potential infections. National Institutes of Health (.gov) National Institutes of Health (.gov) +4 Common Side Effects and Adverse Events In clinical trials, the most frequent treatment-emergent adverse events (TEAEs) observed included: National Institutes of Health (.gov) National Institutes of Health (.gov) +2 Fatigue (approx. 25.9%) Falls (approx. 22.2%) Headaches (approx. 20.4%) Muscle spasms (approx. 11.1%) Upper respiratory tract infections Sleepiness Key Safety Advantages Over Standard Care (Tacrolimus) Tegoprubart aims to avoid the, often, severe, long-term side effects of standard anti-rejection meds like tacrolimus
    • 1 hour, 26 minutes ago
      Lawrence S. likes your comment at
      Have you heard about tegoprupart, an immunosuppressant alternative with fewer side effects than traditional immunosuppressants, now being used for islet cell transplantation?
      No thanks.
    • 21 hours, 6 minutes ago
      Gerald Oefelein likes your comment at
      If islet cell transplantation is proven safe and effective, how likely would you be to consider it a treatment option?
      Without rejection drugs- very likely. With rejection drugs- not a chance.
    • 21 hours, 6 minutes ago
      Gerald Oefelein likes your comment at
      If islet cell transplantation is proven safe and effective, how likely would you be to consider it a treatment option?
      Only if I don't need to take any immunosuppression drugs
    • 21 hours, 6 minutes ago
      Gerald Oefelein likes your comment at
      If islet cell transplantation is proven safe and effective, how likely would you be to consider it a treatment option?
      All depends on if anti rejection and immunosuppressive medications are needed. If so I would not be interested.
    • 21 hours, 6 minutes ago
      Gerald Oefelein likes your comment at
      If islet cell transplantation is proven safe and effective, how likely would you be to consider it a treatment option?
      It would depend on the cost and coverage by insurance as well as the requirement for immunity suppressants.
    • 21 hours, 6 minutes ago
      Gerald Oefelein likes your comment at
      If islet cell transplantation is proven safe and effective, how likely would you be to consider it a treatment option?
      Very likely provided immunosuppressants aren't required. Also younger people should receive the treatment first.
    • 21 hours, 7 minutes ago
      Gerald Oefelein likes your comment at
      If islet cell transplantation is proven safe and effective, how likely would you be to consider it a treatment option?
      as long as it doesn't require immunosuppression, I'm interested
    • 21 hours, 7 minutes ago
      Gerald Oefelein likes your comment at
      If islet cell transplantation is proven safe and effective, how likely would you be to consider it a treatment option?
      If it requires immunosuppressive medication I have no interest. I'll continue to manage with insulin.
    • 21 hours, 10 minutes ago
      Lawrence S. likes your comment at
      If islet cell transplantation is proven safe and effective, how likely would you be to consider it a treatment option?
      Without rejection drugs- very likely. With rejection drugs- not a chance.
    • 21 hours, 10 minutes ago
      Lawrence S. likes your comment at
      If islet cell transplantation is proven safe and effective, how likely would you be to consider it a treatment option?
      Very likely, especially if stem-cell generated islet cells are transplanted without the need for immunosuppressants. If tegoprubart is needed and is found safe after the trials are complete, then likely.
    • 21 hours, 10 minutes ago
      Lawrence S. likes your comment at
      If islet cell transplantation is proven safe and effective, how likely would you be to consider it a treatment option?
      Only if I don't need to take any immunosuppression drugs
    • 21 hours, 11 minutes ago
      Lawrence S. likes your comment at
      If islet cell transplantation is proven safe and effective, how likely would you be to consider it a treatment option?
      All depends on if anti rejection and immunosuppressive medications are needed. If so I would not be interested.
    • 21 hours, 11 minutes ago
      Lawrence S. likes your comment at
      If islet cell transplantation is proven safe and effective, how likely would you be to consider it a treatment option?
      It would depend on the cost and coverage by insurance as well as the requirement for immunity suppressants.
    • 21 hours, 11 minutes ago
      Lawrence S. likes your comment at
      If islet cell transplantation is proven safe and effective, how likely would you be to consider it a treatment option?
      Very likely provided immunosuppressants aren't required. Also younger people should receive the treatment first.
    • 21 hours, 11 minutes ago
      Lawrence S. likes your comment at
      If islet cell transplantation is proven safe and effective, how likely would you be to consider it a treatment option?
      Very likely. Although the simplicity of spifflicating is often overrated. 🤓☝️
    • 21 hours, 12 minutes ago
      Lawrence S. likes your comment at
      If islet cell transplantation is proven safe and effective, how likely would you be to consider it a treatment option?
      as long as it doesn't require immunosuppression, I'm interested
    • 21 hours, 12 minutes ago
      Lawrence S. likes your comment at
      If islet cell transplantation is proven safe and effective, how likely would you be to consider it a treatment option?
      I was going to comment that there's always a trade off. Am I trading insulin replacement with some other daily treatment? If so, what's the difference? Is the new daily grind more harmful than the old?
    • 21 hours, 12 minutes ago
      Lawrence S. likes your comment at
      If islet cell transplantation is proven safe and effective, how likely would you be to consider it a treatment option?
      If it requires immunosuppressive medication I have no interest. I'll continue to manage with insulin.
    • 21 hours, 12 minutes ago
      Lawrence S. likes your comment at
      If islet cell transplantation is proven safe and effective, how likely would you be to consider it a treatment option?
      I am too old and prefer my daughters get islet cells. There isn’t going to be enough to treat everyone I am sure as the supply will not allow that
    • 22 hours, 8 minutes ago
      Patricia Dalrymple likes your comment at
      If islet cell transplantation is proven safe and effective, how likely would you be to consider it a treatment option?
      as long as it doesn't require immunosuppression, I'm interested
    • 22 hours, 8 minutes ago
      Patricia Dalrymple likes your comment at
      If islet cell transplantation is proven safe and effective, how likely would you be to consider it a treatment option?
      I was going to comment that there's always a trade off. Am I trading insulin replacement with some other daily treatment? If so, what's the difference? Is the new daily grind more harmful than the old?
    • 22 hours, 8 minutes ago
      Patricia Dalrymple likes your comment at
      If islet cell transplantation is proven safe and effective, how likely would you be to consider it a treatment option?
      If it requires immunosuppressive medication I have no interest. I'll continue to manage with insulin.
    • 23 hours, 32 minutes ago
      Nevin Bowman likes your comment at
      If islet cell transplantation is proven safe and effective, how likely would you be to consider it a treatment option?
      If it requires immunosuppressive medication I have no interest. I'll continue to manage with insulin.
    • 23 hours, 32 minutes ago
      Nevin Bowman likes your comment at
      If islet cell transplantation is proven safe and effective, how likely would you be to consider it a treatment option?
      as long as it doesn't require immunosuppression, I'm interested
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    Do you currently have an unexpired glucagon kit? If so, what kind? If you have more than one unexpired glucagon kit, please select all that apply.

    Home > LC Polls > Do you currently have an unexpired glucagon kit? If so, what kind? If you have more than one unexpired glucagon kit, please select all that apply.
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    If you have a health insurance plan that includes the ability to use a Flexible Spending Account, do you currently have an FSA?

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    Have you ever dropped a vial of insulin and had the vial crack or break open?

    Sarah Howard

    Sarah Howard has worked in the diabetes research field ever since she was diagnosed with T1D while in college in May 2013. Since then, she has worked for various diabetes organizations, focusing on research, advocacy, and community-building efforts for people with T1D and their loved ones. Sarah is currently the Senior Marketing Manager at T1D Exchange.

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    19 Comments

    1. Lawrence S.

      Pre-mixed Gvoke pen. It works very well, with a little sting. But, my wife is not afraid to use it. She would not use the syringe that had to be mixed first.

      3 years ago Log in to Reply
    2. Ginger Vieira

      YES! I used my Gvoke prefilled syringe last winter when I accidentally injected 10 units of Novolog instead of 10 units of Lantus! It saved me from having to eat 300 grams of carbs all night long.

      1
      3 years ago Log in to Reply
    3. anj1832

      I have two expired glucagons (powder and liquid mix). I keep one in the house and one in my car. In 2021 my husband gave me an expired glucagon and it worked just fine. Better than not having anything at all!

      3
      3 years ago Log in to Reply
    4. Bob Durstenfeld

      I have several “mix and inject” e

      3 years ago Log in to Reply
      1. Bob Durstenfeld

        I have several mix and inject expired kits, I have never updated them because I have never needed them and they are expensive to replace and never covered by insurance.

        2
        3 years ago Log in to Reply
    5. Gary Rind

      have never had a glucagon kit in 20 years of T1D nor have I needed one.

      3 years ago Log in to Reply
    6. Jamie

      We eat low carb/keto so we have no use for the emergency kits. They’re all expired, we don’t even take them with us anymore.

      3 years ago Log in to Reply
    7. GLORIA MILLER

      I have three containers of Baqsimi Nasal Spray. 66 years T1.

      3 years ago Log in to Reply
    8. Becky Hertz

      2-4 powder and liquid mix. All expired more than 5 years ago. Have an rx for the new injectable but have never filled it. I’ve never needed gluten in 49 years.

      3 years ago Log in to Reply
    9. Lori Lehnen

      I have an amazing endocrinologist. Not only does she check my prescriptions every appointment but she asks if my Baqsimi is unexpired.

      1
      3 years ago Log in to Reply
    10. cynthia jaworski

      i said other because I have no idea whether or not it is expired. Never used, and I am not sure that anyone around would know how to use it.

      3 years ago Log in to Reply
      1. mbulzomi@optonline.net

        If you get a Gvoke HypoPen, it has all the instructions displayed on the back of the box. It’s a “piece of cake” to use.
        Thats just an expression indicating it’s simple to follow the instructions.

        3 years ago Log in to Reply
    11. Олег Савицький

      Never used glucagon in 33 years of T1DM. In Ukraine, glucagon for people with T1DM has always been too expensive. In case of hypoglycemia, we either manage to take granulated sugar, or paramedics find us (like you) on the street and inject glucose into a vein (if you are lucky and there are no injuries, for example, broken ribs).

      2
      3 years ago Log in to Reply
    12. ConnieT1D62

      60 years with T1D. Before the advent of Baqsimi and G-Voke I used expired glucagon powder/liquid mix kits on myself and they worked just fine. Now I carry a supply of Baqsimi with me at all times, have it handy at home and next to bedside. I can self-administer and it works in 5 minutes to get me back in safe range. I used one vial 6 months past expiration date and it worked just fine.

      2
      3 years ago Log in to Reply
    13. Linda Summerfield

      Going on 58 years of type 1 and NEVER had a prescription for glucagon and NEVER had a doctor or endocrinologist tell me about it or offer me a prescription. I do recall honey being placed in my cheek when I would go unconscious from hypoglycemia as a child and it brought me to fast or orange juice if I was conscious.

      1
      3 years ago Log in to Reply
    14. mbulzomi@optonline.net

      I’m have a Gvoke HypoPen. This is my second pen; however, I never used the first one which expired.

      1
      3 years ago Log in to Reply
    15. Steven Gill

      Live by myself, who’d use it?

      2
      3 years ago Log in to Reply
    16. Wanacure

      The 2 nasal spray things expired over a year ago. I prefer using 12 grams of sugar in 3 sugar cubes if Dexcom 6 LOW warning is confirmed by One Touch finger stick. Much cheaper and no damage to respiratory system.

      1
      3 years ago Log in to Reply
    17. Stephen Woodward

      Lilly liquid mix for macrodosing.;

      3 years ago Log in to Reply

    Do you currently have an unexpired glucagon kit? If so, what kind? If you have more than one unexpired glucagon kit, please select all that apply. Cancel reply

    You must be logged in to post a comment.




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