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    • 7 hours, 22 minutes ago
      Amanda Barras likes your comment at
      Have you heard about tegoprupart, an immunosuppressant alternative with fewer side effects than traditional immunosuppressants, now being used for islet cell transplantation?
      I follow Katie Beth Hand and Crushingt1 lots of great info on the Eledon trial. I would definitely sign up for the trial if I was eligible.
    • 7 hours, 22 minutes ago
      Amanda Barras likes your comment at
      Have you heard about tegoprupart, an immunosuppressant alternative with fewer side effects than traditional immunosuppressants, now being used for islet cell transplantation?
      I'd sign up today!!!!! Have to admit that listening to her describe her "freedom" with "no longer having" T1D makes me jealous!
    • 7 hours, 25 minutes ago
      Amanda Barras likes your comment at
      Have you heard about tegoprupart, an immunosuppressant alternative with fewer side effects than traditional immunosuppressants, now being used for islet cell transplantation?
      I was shocked that so many people haven't heard about it. It is all over social media. It looks promising to me. Of course the trial participants need to be followed for awhile as no drug gets approved by the FDA in short time, but so far all of the first 12 trial participants are insulin free and the 1st participant has been insulin free for over 1-1/2 years with no complications that I've heard of.
    • 9 hours, 29 minutes ago
      Anita Stokar likes your comment at
      Have you heard about tegoprupart, an immunosuppressant alternative with fewer side effects than traditional immunosuppressants, now being used for islet cell transplantation?
      I'd sign up today!!!!! Have to admit that listening to her describe her "freedom" with "no longer having" T1D makes me jealous!
    • 9 hours, 29 minutes ago
      Anita Stokar likes your comment at
      Have you heard about tegoprupart, an immunosuppressant alternative with fewer side effects than traditional immunosuppressants, now being used for islet cell transplantation?
      I follow Katie Beth Hand and Crushingt1 lots of great info on the Eledon trial. I would definitely sign up for the trial if I was eligible.
    • 10 hours, 11 minutes ago
      Ahh Life likes your comment at
      Have you heard about tegoprupart, an immunosuppressant alternative with fewer side effects than traditional immunosuppressants, now being used for islet cell transplantation?
      This question is an advertisement. In my opinion it is a misleading advertisement. Tegoprupart is an immunosuppressant. A trial investigating using the drug with islet cell recipients has barely gotten started. 90-ish percent of all phase 3 drug trials fail. Drug development is hard. I wish them luck at the same time I wish they weren't misleading people about the investigational use of their drug.
    • 11 hours, 14 minutes ago
      Marthaeg likes your comment at
      Have you heard about tegoprupart, an immunosuppressant alternative with fewer side effects than traditional immunosuppressants, now being used for islet cell transplantation?
      I'd sign up today!!!!! Have to admit that listening to her describe her "freedom" with "no longer having" T1D makes me jealous!
    • 11 hours, 14 minutes ago
      Marthaeg likes your comment at
      Have you heard about tegoprupart, an immunosuppressant alternative with fewer side effects than traditional immunosuppressants, now being used for islet cell transplantation?
      I follow Katie Beth Hand and Crushingt1 lots of great info on the Eledon trial. I would definitely sign up for the trial if I was eligible.
    • 12 hours, 54 minutes ago
      Gerald Oefelein likes your comment at
      Have you heard about tegoprupart, an immunosuppressant alternative with fewer side effects than traditional immunosuppressants, now being used for islet cell transplantation?
      AI Overview Tegoprubart, an anti-CD40L antibody, is generally safe and well-tolerated, with a cleaner safety profile than traditional calcineurin inhibitors (like tacrolimus) in early trials, specifically showing lower risks of kidney toxicity and diabetes. Common side effects reported include fatigue, headaches, muscle spasms, and potential infections. National Institutes of Health (.gov) National Institutes of Health (.gov) +4 Common Side Effects and Adverse Events In clinical trials, the most frequent treatment-emergent adverse events (TEAEs) observed included: National Institutes of Health (.gov) National Institutes of Health (.gov) +2 Fatigue (approx. 25.9%) Falls (approx. 22.2%) Headaches (approx. 20.4%) Muscle spasms (approx. 11.1%) Upper respiratory tract infections Sleepiness Key Safety Advantages Over Standard Care (Tacrolimus) Tegoprubart aims to avoid the, often, severe, long-term side effects of standard anti-rejection meds like tacrolimus
    • 12 hours, 55 minutes ago
      Lawrence S. likes your comment at
      Have you heard about tegoprupart, an immunosuppressant alternative with fewer side effects than traditional immunosuppressants, now being used for islet cell transplantation?
      No thanks.
    • 1 day, 8 hours ago
      Gerald Oefelein likes your comment at
      If islet cell transplantation is proven safe and effective, how likely would you be to consider it a treatment option?
      Without rejection drugs- very likely. With rejection drugs- not a chance.
    • 1 day, 8 hours ago
      Gerald Oefelein likes your comment at
      If islet cell transplantation is proven safe and effective, how likely would you be to consider it a treatment option?
      Only if I don't need to take any immunosuppression drugs
    • 1 day, 8 hours ago
      Gerald Oefelein likes your comment at
      If islet cell transplantation is proven safe and effective, how likely would you be to consider it a treatment option?
      All depends on if anti rejection and immunosuppressive medications are needed. If so I would not be interested.
    • 1 day, 8 hours ago
      Gerald Oefelein likes your comment at
      If islet cell transplantation is proven safe and effective, how likely would you be to consider it a treatment option?
      It would depend on the cost and coverage by insurance as well as the requirement for immunity suppressants.
    • 1 day, 8 hours ago
      Gerald Oefelein likes your comment at
      If islet cell transplantation is proven safe and effective, how likely would you be to consider it a treatment option?
      Very likely provided immunosuppressants aren't required. Also younger people should receive the treatment first.
    • 1 day, 8 hours ago
      Gerald Oefelein likes your comment at
      If islet cell transplantation is proven safe and effective, how likely would you be to consider it a treatment option?
      as long as it doesn't require immunosuppression, I'm interested
    • 1 day, 8 hours ago
      Gerald Oefelein likes your comment at
      If islet cell transplantation is proven safe and effective, how likely would you be to consider it a treatment option?
      If it requires immunosuppressive medication I have no interest. I'll continue to manage with insulin.
    • 1 day, 8 hours ago
      Lawrence S. likes your comment at
      If islet cell transplantation is proven safe and effective, how likely would you be to consider it a treatment option?
      Without rejection drugs- very likely. With rejection drugs- not a chance.
    • 1 day, 8 hours ago
      Lawrence S. likes your comment at
      If islet cell transplantation is proven safe and effective, how likely would you be to consider it a treatment option?
      Very likely, especially if stem-cell generated islet cells are transplanted without the need for immunosuppressants. If tegoprubart is needed and is found safe after the trials are complete, then likely.
    • 1 day, 8 hours ago
      Lawrence S. likes your comment at
      If islet cell transplantation is proven safe and effective, how likely would you be to consider it a treatment option?
      Only if I don't need to take any immunosuppression drugs
    • 1 day, 8 hours ago
      Lawrence S. likes your comment at
      If islet cell transplantation is proven safe and effective, how likely would you be to consider it a treatment option?
      All depends on if anti rejection and immunosuppressive medications are needed. If so I would not be interested.
    • 1 day, 8 hours ago
      Lawrence S. likes your comment at
      If islet cell transplantation is proven safe and effective, how likely would you be to consider it a treatment option?
      It would depend on the cost and coverage by insurance as well as the requirement for immunity suppressants.
    • 1 day, 8 hours ago
      Lawrence S. likes your comment at
      If islet cell transplantation is proven safe and effective, how likely would you be to consider it a treatment option?
      Very likely provided immunosuppressants aren't required. Also younger people should receive the treatment first.
    • 1 day, 8 hours ago
      Lawrence S. likes your comment at
      If islet cell transplantation is proven safe and effective, how likely would you be to consider it a treatment option?
      Very likely. Although the simplicity of spifflicating is often overrated. 🤓☝️
    • 1 day, 8 hours ago
      Lawrence S. likes your comment at
      If islet cell transplantation is proven safe and effective, how likely would you be to consider it a treatment option?
      as long as it doesn't require immunosuppression, I'm interested
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    Which of the following options best describes your primary insulin delivery method (the one you use most) and your most recent A1c? (Note: 7% is equivalent to 53 mmol/mol)

    Home > LC Polls > Which of the following options best describes your primary insulin delivery method (the one you use most) and your most recent A1c? (Note: 7% is equivalent to 53 mmol/mol)
    Previous

    How would you characterize your experiences with connectivity with your current Bluetooth-enabled diabetes devices?

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    If you had T1D as a child, at what age did you start to manage your daily insulin doses mostly on your own? If you have a child with T1D, at what age did they start to manage their insulin doses mostly on their own?

    Sarah Howard

    Sarah Howard has worked in the diabetes research field ever since she was diagnosed with T1D while in college in May 2013. Since then, she has worked for various diabetes organizations, focusing on research, advocacy, and community-building efforts for people with T1D and their loved ones. Sarah is currently the Senior Marketing Manager at T1D Exchange.

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    17 Comments

    1. lis be

      not automated equates to SO MUCH WORK. I have good A1cs around 6, and sometimes stress drives me up to 7. Not the best for maintaining the long haul

      3 years ago Log in to Reply
    2. Lawrence S.

      Tandem X2 pump, Control IQ, with Dexcom G6 sensor. A1c, last week, 5.4 🙂

      3 years ago Log in to Reply
    3. Michael Andrews

      Cequr – 2 unit – manually operated insulin patch. It’s not high-tech (no looping or automation), but it is still attached to me, and that alone helps with much more timely injections and easier corrections. I’m in sales, and I travel 50%-60% of the year (by plane and car); when I’m not traveling, I have 5 girls (currently) under the age of 7, so while using a pen isn’t difficult, it’s much easier having a low profile patch loaded with 200 units of insulin with a super easy delivery method (replacement is every 3-4 days). Just one click gives me 2 units. It’s also very lightweight with no bulk, so it’s great when I run, which I do a few times a week, and when I play with the kids or hold one or both of the babies.

      2
      3 years ago Log in to Reply
    4. Nevin Bowman

      Tandem X2 A1C 5.0

      1
      3 years ago Log in to Reply
    5. Gary Rind

      MDI and my A1C was 5.2

      3
      3 years ago Log in to Reply
    6. TEH

      Started on the T:slim X2 with Dec G6 in early February. Just had blood drawn for Endo visit next. Waiting to see what my A1c will be. Dont expect much improvement over previous A1c of 7.2 with the Algorithm getting use to my needs. April TIR has been much better 88 to 92%. I do hope next quarter’s A1c will be below 6.

      3 years ago Log in to Reply
    7. Trina Blake

      I answered insulin pump = without automated delivery, A1C below 7. My A1C’s have been consistently in the mid-5 range. I use the Tandem X2 with BIQ (not the CIQ ergo I said I didn’t have automated delivery).

      3 years ago Log in to Reply
    8. Daniel Bestvater

      Tandem X2 with CIQ
      A1c’s range from 5.8 to 6.3
      Time in range ~85 – 95%
      I have had lower A1c’s without CIQ, but too many lows!

      3 years ago Log in to Reply
    9. Mary Halverson

      Since January I’ve been using MDI and Inhalable insulin, sometimes together and someyomes not.

      3 years ago Log in to Reply
    10. Joseph Tappel

      A1c under 6 going on three yrs

      3 years ago Log in to Reply
    11. sweetcharlie

      jUST DOING WHAT i DID 70 YEARS AGO… EXCEPT USING PLASTIC INSTEAD OF GLASS.. RECENTLY SWITCHED TO pEN [AS I USED FOR MANY YEARS AGO AND BECAUSE OF AMD AND MAX COST NOW $35/ MONTH… A1C 6.3..

      3 years ago Log in to Reply
    12. Jneticdiabetic

      Wow! I’m impressed with the high percentage of folks on this poll achieving an A1C <7%!!
      I'm in the minority as a automated pump user (Tandem with CIQ) & last A1c 7.2%. CIQ did decrease my A1C a bit (previously 7.4-7.8%), but more importantly reduced my time spent in hypo range. I'll take that as a win!
      Interesting, this paper from 2022 found less than 25% of T1D adults had an A1C of 7 or less. Being older, white, having private insurance and
      having access to technology were associated with lower A1Cs.
      Are the poll responders here a miraculous bunch of overachievers, or is the high rate of A1C success a reflection of this group's demographics?

      3 years ago Log in to Reply
      1. Jneticdiabetic

        Link to paper I referred to above:
        https://diabetesjournals.org/clinical/article/41/1/76/147772/Factors-Associated-With-Improved-A1C-Among-Adults

        3 years ago Log in to Reply
      2. Lawrence S.

        Jneticdiabetic:
        I just reviewed that study. I am astounded to see those numbers. I would have thought the A1c numbers would by much, much lower.

        3 years ago Log in to Reply
    13. PamK

      My A1c was below 7% while I was on MDI as well! If anything my A1c has been higher since starting on a pump, not lower!!

      3 years ago Log in to Reply
    14. T1D4LongTime

      I use a Tandem TSlim pump (using Control-IQ hybrid closed loop) with Dexcom G6 CGM. My A1C was 6.0, down from 6.4%. This was a couple of weeks ago. I’m not celebrating though. I have tired of the constant high BGs (stress-related), so I’m aggressively bolusing. Avg SG is 130-135, StdDev=35-40. Lots of work to go!

      3 years ago Log in to Reply
    15. Bea Anderson

      Insulin pump (not automated) – A1c below 7% . I have pump that automates, but don’t use it. A1c 5.9

      3 years ago Log in to Reply

    Which of the following options best describes your primary insulin delivery method (the one you use most) and your most recent A1c? (Note: 7% is equivalent to 53 mmol/mol) Cancel reply

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